THE HUMAN PATHOGEN MYCOBACTERIUM TUBERCULOSIS AND THE FISH PATHOGEN MYCOBACTERIUM MARINUM TRIGGER A CORE SET OF LATE INNATE IMMUNE RESPONSE GENES IN ZEBRAFISH LARVAE

Zebrafish is a natural host of various Mycobacterium species and a surrogate model organism for tuberculosis research.Mycobacterium marinum is bostik universal primer pro evolutionarily one of the closest non-tuberculous species related to M.tuberculosis and shares the majority of virulence genes.Although zebrafish is not a natural host of the huma

Aging-associated alterations of cellular truvisionhealthftp.com functions have been implicated in various disorders including cancers.Due to difficulties in identifying aging cells in living tissues, most studies have focused on aging-associated changes in whole tissues or certain cell pools.Thus, it remains unclear what kinds of alterations accumu

Autosomal recessive polycystic kidney disease is a truly catastrophic monogenetic disease, causing death and end stage renal disease in neonates and children.Using PCK female rats, an orthologous model of autosomal recessive polycystic kidney disease harboring mutant Pkhd1, we tested the hypothesis that intravenous renal cell transplantation with n

Isosmotic oral agents are commonly used in bowel preparation due to their minimal side effects.However, bowel perforation is a rare and severe complication.Connective tissue disease and medications such as nonsteroidal anti-inflammatory drugs/steroids can weaken the colonic wall, which increases the risk of perforation.We present a silver lining he

BackgroundExpression of autonomous bioluminescence from human cells was previously reported to be impossible, suggesting that all bioluminescent-based mammalian reporter systems must therefore require application of a potentially influential chemical substrate.While this was disproven when the bacterial luciferase (lux) cassette was demonstrated to